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SiliaPrep Silica-based SPE Cartridges & Well Plates

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Reversed-Phases Normal Phases Ion-Exchange Phases Mixed-Mode Phases

Metal Scavengers Fluorinated Phases Specialty Phases

Solid-phase extraction (SPE) is a technique designed for rapid sample preparation and purification prior to chromatographic analysis.

For your convenience, SiliaPrep are available in different formats: cartridges (SiliaPrep SPE Cartridges), and well plates (SiliaPrep 96 Well Plates) with various sorbents (SiliaFlash® and SiliaBond®), and bed weight (up to 20 grams). The well plates are used in high throughput combinatorial chemistry, drug discovery and screening, and metabolism pharmacokinetics applications and for automated method as multiprobe approach.

By using SiliaPrep products you will generate higher purity samples and reduce the number of false positives in your screening, resulting in higher quality data. All the SiliaPrep are packed with sorbents based on the fines-free SiliaFlash silica gel.

Using SiliaPrep will guarantee the following:

  • High quality and wide variety of SiliaBond sorbents available
  • Very good separation (very tight particle size distribution and no fines)
  • High recoveries and yields
  • Less time and solvent spent conditioning the sorbent
  • No silica contamination of your final product
  • Reproducible flow rate from lot-to-lot
  • Excellent packing and storage qualities

 

 NEW  Learn more about using our SiliaPrep SPE products with our Suggested SPE protocols for various analytes & matrices

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  1. SiliaSep OT Flash Cartridges (Open Top), Carbonate, 40 - 63 µm, 60 Å (FLH-R66030B-OT)

    SiliaSep OT Flash Cartridges, Carbonate, 40 - 63 µm, 60 Å (FLH-R66030B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument.
  2. SiliaPrep SPE Cartridges Silica (SPE-R10030B)

    SiliaPrep SPE Cartridges, Silica, 40 - 63 µm, 60 Å (SPE-R10030B)

    SiliaPrep Silica is the most polar sorbent presenting a slightly acidic character used to extract various compounds from non-polar solvents using hydrogen bonding. Efficient sorbent for the separation of analytes with similar structures and for removing the baseline noise from organic samples.
  3. SiliaPrep SPE Cartridges Amine (WAX) (SPE-R52030B)

    SiliaPrep SPE Cartridges Amine (WAX) (SPE-R52030B)

    SiliaPrep Amine is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and in normal phase conditions.
  4. SiliaPrep SPE Cartridges Amine (WAX) nec (SPE-R52130B)

    SiliaPrep SPE Cartridges Amine (WAX) nec (SPE-R52130B)

    SiliaPrep Amine nec is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and norman phase conditions.
  5. SiliaPrep SPE Cartridges, Carboxylic Acid (WCX) (SPE-R70030B)

    SiliaPrep SPE Cartridges, Carboxylic Acid (WCX) (SPE-R70030B)

    SiliaPrep Carboxylic Acid is a weak cation exchanger sorbent (WCX) used to extract strong basic compounds.
  6. SiliaPrep SPE Cartridges Carboxylic Acid (WCX) nec (SPE-R70130B)

    SiliaPrep SPE Cartridges, Carboxylic Acid (WCX) nec (SPE-R70130B)

    SiliaPrep Carboxilic Acid nec is a weak cation exchanger sorbent (WCX) used to extract strong basics compounds.
  7. SiliaPrep SPE Cartridges Cyano (CN) (SPE-R38030B)

    SiliaPrep SPE Cartridges Cyano (CN) (SPE-R38030B)

    SiliaPrep Cyano is a moderate polar sorbent used as reversed-phase (less hydrophobic than C18 and C8 phases) and normal phase (less polar compared to silica) to extract acidic, neutral, basic compounds from aqueous solutions.
  8. SiliaPrep SPE Cartridges Diol (SPE-R35030B)

    SiliaPrep SPE Cartridges Diol nec (SPE-R35030B)

    SiliaPrep Diol nec is a moderate polar sorbent presenting neutral character used to extract polar compounds from non-polar solvents, structural isomers. Alternative to silica when the acidic character is problematic.
  9. SiliaPrep SPE Cartridges C1 (SPE-R33030B)

    SiliaPrep SPE Cartridges C1 (SPE-R33030B)

    SiliaPrep C1 is a non-polar sorbent and presents a mederate hydrophobicity. This phase is used to extract extremely non-polar compounds.
  10. SiliaPrep SPE Cartridges C2 (SPE-R32530B)

    SiliaPrep SPE Cartridges C2 (SPE-R32530B)

    SiliaPrep C2 is a non-polar sorbent and presents a moderate hydrophobicity. This phase is used to extract extremely non-polar compounds.
  11. SiliaPrep SPE Cartridges C2 nec (SPE-R32630B)

    SiliaPrep SPE Cartridges C2 nec (SPE-R32630B)

    SiliaPrep C2 nec is a non-polar sorbent and presents a moderate hydrophobicity. This phase is used to extract extremely non-polar compounds.
  12. SiliaPrep SPE Cartridges C4 (SPE-R32030B)

    SiliaPrep SPE Cartridges C4 (SPE-R32030B)

    Present less retention compared to C18 and C8. Widely used for molecules with large hydrophobic regions.
  13. SiliaPrep SPE Cartridges C8 (SPE-R31030B)

    SiliaPrep SPE Cartridges C8 (SPE-R31030B)

    SiliaPrep C8 is a non-polar sorbent and presents a moderate hydrophobicity. This phase is used to extract extremely non-polar compounds. SiliaPrep C8 is more selective than the C18 phase for compounds such as heavy PAH, vitamins D and oil & greasy compounds.
  14. SiliaPrep SPE Cartridges C18 (17%) nec (SPE-R35530B)

    SiliaPrep SPE Cartridges C18 (17%) nec (SPE-R35530B)

    SiliaPrep C18 (17%) nec is a non-polar sorbent similar to SiliaPrep C18 but presents higher retention and polar selectivity for basic compounds.
  15. SiliaPrep SPE Cartridges Phenyl (PH) (SPE-R34030B)

    SiliaPrep SPE Cartridges Phenyl (PH) (SPE-R34030B)

    SiliaPrep Phenyl is a non-polar sorbent used to extract compounds from aqueous solution and presents high selectivity for aromatics compounds compared to the other non-polar phases caused by the pi-pi interactions.
  16. SiliaPrep SPE Cartridges Triethylamine (WAX-2) (SPE-R76530B)

    SiliaPrep SPE Cartridges, Triethylamine (WAX-2) (SPE-R76530B)

    SiliaPrep Triethylamine (WAX-2) is a weak anion exchanger that can be used in replacement of SAX and SAX-2 for strong anions to avoid irreversible retention. This phase presents a slightly lower capacity and a moderate non polar character due to the alkyl chain on the amino function. Moreover, it can be employed as metal scavenger and in normal phase conditions.
  17. SiliaPrep SPE Cartridges, Pentafluoprophenyl (PFP) (SPE-R67530B)

    SiliaPrep SPE Cartridges, Pentafluoprophenyl (PFP) (SPE-R67530B)

    SiliaPrep Pentafluorophenyl is a fluorous sorbent used to separate fluorinated molecules and non-fluorinated ones. The electron density presents fluorinated aromatic ring which affords an enhancement in the retention of conjugated and aromatic ring-containing due to the desirable pi-pi interactions. Excellent alternative of the C18 when the C18 presents a selectivity problem.
  18. SiliaPrep SPE Cartridges Fluorochrom (SPE-R63730B)

    SiliaPrep SPE Cartridges Fluorochrom (SPE-R63730B)

    SiliaPrep Fluorochrom is a fluorous sorbent used to separate fluorinated molecules and non-fluorinated ones.
  19. SiliaPrep SPE Cartridges Tridecafluoro (SPE-R63530B)

    SiliaPrep SPE Cartridges Tridecafluoro (SPE-R63530B)

    SiliaPrep Tridecafluoro is a fluorous sorbent used to separate fluorinated molecules and non-fluorinated ones.
  20. SiliaPrep SPE Cartridges, TMA Chloride (SAX) nec (SPE-R66530B)

    SiliaPrep SPE Cartridges, TMA Chloride (SAX) nec (SPE-R66530B)

    SiliaPrep TMA Chloride (SAX) is a strong anion exchanger sorbent positively charged under all conditions used to extract acid molecules (pKa 3-5).
  21. SiliaPrep SPE Cartridges, TMA Acetate (SAX-2) nec (SPE-R66430B)

    SiliaPrep SPE Cartridges, TMA Acetate (SAX-2) nec (SPE-R66430B)

    SiliaPrep TMA Acetate (SAX-2) is a strong anion exchanger sorbent with a low selectivity acetate counter ion already in place. This sorbent retains more favorably acidic compounds with pKas <5, such as carboxylic acid.
  22. SiliaPrep SPE Cartridges Tosic Acid (SCX) (SPE-R60530B)

    SiliaPrep SPE Cartridges Tosic Acid (SCX) (SPE-R60530B)

    SiliaPrep Tosic Acid (SCX) is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  23. SiliaPrep SPE Cartridges Tosic Acid (SCX) nec (SPE-R60430B)

    SiliaPrep SPE Cartridges Tosic Acid (SCX) nec (SPE-R60430B)

    SiliaPrep Tosic Acid is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  24. SiliaPrep SPE Cartridges Propylsulfonic Acid (SCX-2) (SPE-R51230B)

    SiliaPrep SPE Cartridges Propylsulfonic Acid (SCX-2) (SPE-R51230B)

    SiliaPrep Propylsulfonic Acid (SCX-2) is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  25. SiliaPrep SPE Cartridges Propylsulfonic Acid (SCX-2) nec (SPE-R51430B)

    SiliaPrep SPE Cartridges Propylsulfonic Acid (SCX-2) nec (SPE-R51430B)

    SiliaPrep Propylsulfonic Acid nec is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  26. SiliaPrep SPE Cartridges Florisil, 40 - 75 µm, 100 Å (SPE-AUT-0014)

    SiliaPrep SPE Cartridges Florisil, 40 - 75 µm, 80 Å (SPE-AUT-0014)

    SiliaPrep Florisil is a polar sorbent presenting basic character used to extract non-polar to moderate polar compounds from non-polar solvents. This sorbent contain magnesium ion which allows retention for chlorinated pesticides, polychlorinated biphenyl and polysaccharides.
  27. SiliaPrep SPE Cartridges Florisil PR Grade, 150 - 250 µm, 100 Å (SPE-AUT-0015)

    SiliaPrep SPE Cartridges Florisil PR Grade, 150 - 250 µm (SPE-AUT-0015)

    SiliaPrep Florisil is a polar sorbent presenting basic character used to extract non-polar to moderate polar compounds from non-polar solvents. This sorbent contain magnesium ion which allows retention for chlorinated pesticides.
  28. SiliaPrep SPE Cartridges Acidic Alumina, 75 - 150 µm, 70 Å (SPE-AUT-0053)

    SiliaPrep SPE Cartridges Acidic Alumina, 75 - 150 µm (SPE-AUT-0053)

    SiliaPrep Acidic Alumina is a polar sorbent basic character used to extract compounds as described for SiliaPrep Silica. SiliPrep Acidic Alumina is more stable at high pH than silica.
  29. SiliaPrep SPE Cartridges Neutral Alumina, 75 - 150 µm, 70 Å (SPE-AUT-0054)

    SiliaPrep SPE Cartridges Neutral Alumina, 75 - 150 µm (SPE-AUT-0054)

    SiliaPrep Neutral Alumina is a polar sorbent basic character used to extract compounds as described for SiliaPrep Silica. SiliaPrep Neutral Alumina is more stable at high pH than silica.
  30. SiliaPrep SPE Cartridges Basic Alumina (SPE-AUT-0055)

    SiliaPrep SPE Cartridges Basic Alumina (SPE-AUT-0055)

    SiliaPrep Basic Alumina is a polar sorbent basic character used to extract compounds as described for SiliaPrep Silica. SiliaPrep Basic Alumina is more stable at high pH than silica.
  31. SiliaPrep Mixed-Mode SPE Cartridges C8/SAX (SPM-R022830B)

    SiliaPrep Mixed-Mode SPE Cartridges, C8/SAX (SPM-R022830B)

    SiliaPrep C8/SAX is a mixed-mode used to extract acidic compounds from aqueous solutions, typically drugs and metabolites from physiological fluids.
  32. SiliaPrep Mixed-Mode SPE Cartridges C8/TMA Acetate (SAX-2) nec (SPM-R026630B)

    SiliaPrep Mixed-Mode SPE Cartridges, C8/SAX-2 nec (SPM-R026630B)

    SiliaPrep C8/SAX-2 is a mixed-mode used to extract acidic compounds from aqueous solutions, typically drugs and metabolites from physiological fluids.
  33. SiliaPrep Mixed-mode SPE Cartridges C8/SCX-2 (SPM-R028030B)

    SiliaPrep Mixed-mode SPE Cartridges, C8/SCX-2 (SPM-R028030B)

    SiliaPrep C8/SCX-2 is a mixed-mode sorbent used to extract basic compounds from aqueous solutions, typically drugs and metabolites from physiological fluids.
  34. SiliaPrep Mixed-Mode SPE Cartridges SCX-2/SAX (SPM-R802830B)

    SiliaPrep Mixed-Mode SPE Cartridges, SCX-2/SAX (SPM-R802830B)

    SiliaPrep SCX-2/SAX is a mixed-mode used to separate acidic and basic molecules from non-ionisable molecules.
  35. SiliaPrep Mixed-Mode SPE Cartridges C8/SCX-2/SAX (SPM-R02802830B)

    SiliaPrep Mixed-Mode SPE Cartridges, C8/SCX-2/SAX (SPM-R02802830B)

    SiliaPrep C8/SCX-2/SAX is a tri-mode extraction and fractionation of acidic, neutral and basic compounds from aqueous solutions, typically drugs and metabolites from physiological fluids.
  36. SiliaPrep Mixed-mode SPE Cartridges C8/SCX-2/TMA Acetate nec (SPM-R02806630B)

    SiliaPrep Mixed-mode SPE Cartridges, C8/SCX-2/SAX-2 nec (SPM-R02806630B)

    SiliaPrep C8/SCX-2/SAX-2 is a tri-mode extraction and fractionation of acidic, neutral and basic compounds from aqueous solutions, typically drugs and metabolites from physiological fluids.
  37. SiliaPrep Mixed-Mode SPE Cartridges C8/SCX (SPM-R023830B)

    SiliaPrep Mixed-Mode SPE Cartridges, C8/SCX (SPM-R023830B)

    SiliaPrep C8/SCX is a mixed-mode sorbent used to extract basic compounds from aqueous solutions, typically drugs and metabolites from physiological fluids.
  38. SiliaPrep SPE Cartridges, Carbonate (SPE-R66030B)

    SiliaPrep SPE Cartridges, Carbonate (SPE-R66030B)

    SiliaPrep Carbonate (or Si-CO3) is the silica bound equivalent of tetramethyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids, boronic acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions.
  39. SiliaPrep SPE Cartridges Diamine (SPE-R49030B)

    SiliaPrep SPE Cartridges Diamine (SPE-R49030B)

    SiliaPrep Diamine can be used in replacement of SAX for strong anions. It can also be employed as metal scavenger and in normal phase conditions. Best scavenger for: Cr, Pd & Pt. Good scavenger for: Cd, Co, Cu, Fe, Hg, Ni, Pb, Ru, W & Zn.

  40. SiliaPrep SPE Cartridges Diamine nec (SPE-R49130B)

    SiliaPrep SPE Cartridges Diamine nec (SPE-R49130B)

    SiliaPrep Diamine can be used in replacement of SAX for strong anions. It can also be employed as metal scavenger and in normal phase conditions. Best scavenger for: Cr, Pd & Pt. Good scavenger for: Cd, Co, Cu, Fe, Hg, Ni, Pb, Ru, W & Zn.

  41. SiliaPrep SPE Cartridges Triamine (SPE-R48030B)

    SiliaPrep SPE Cartridges Triamine (SPE-R48030B)

    Best scavenger for: Cr, Pd, Pt, W & Zn / Good scavenger for: Ag, Cd, Co, Cu, Fe, Hg, Ni, Os, Pb, Ru & Sc
  42. SiliaPrep SPE Cartridges Thiol (SPE-R51030B)

    SiliaPrep SPE Cartridges Thiol (SPE-R51030B)

    Best scavenger for: Ag, Hg, Os, Pd & Ru / Good scavenger for: Cu, Ir, Pb, Rh & Sn
  43. SiliaPrep SPE Cartridges Thiourea (SPE-R69530B)

    SiliaPrep SPE Cartridges, Thiourea (SPE-R69530B)

    Best scavenger for: Pd & Ru / Good scavenger for: Ag, Cu, Fe, Os, Rh, Sc & Sn
  44. SiliaPrep SPE Cartridges, TAAcOH (SPE-R69030B)

    SiliaPrep SPE Cartridges, TAAcOH (SPE-R69030B)

    Best scavenger for: Ca, Co, Ir, Li, Mg, Ni, Os, Ru & Sc / Good scavenger for: Cr, Cs, Fe, Pd, Rh & Sn
  45. SiliaPrep SPE Cartridges, TAAcONa (SPE-R69230B)

    SiliaPrep SPE Cartridges, TAAcONa (SPE-R69230B)

    Best scavenger for: Ca, Cd, Cs, Cu, Fe, Ir, La, Li, Mg, Ni, Os, Rh, Sc & Sn / Good scavenger for: Cr, Pd, Ru, Se & Zn
  46. SiliaPrep SPE Cartridges, Dimercaptotriazine (DMT) (SPE-R79030B)

    SiliaPrep SPE Cartridges, Dimercaptotriazine (DMT) (SPE-R79030B)

    Best scavenger: Ir, Ni, Os, Pd, Pt, Rh, Se & Ru / Good scavenger: Cd, Co, Cu, Fe, Sc & Zn
  47. SiliaPrep SPE Cartridges CleanDRUG (SPEC-R651230B)

    SiliaPrep SPE Cartridges, CleanDRUG (SPEC-R651230B)

    SiliaPrep CleanDRUG phase has been optimized for drugs of abuse applications
  48. SiliaPrep SPE Cartridges CleanENVI (SPEC-R31930B)

    SiliaPrep SPE Cartridges CleanENVI (SPEC-R31930B)

    SiliaPrep CleanENVI phase has been optimized for typical environment samples according to the EPA regulations.
  49. SiliaPrep 96 Well Plates, Silica, 40 - 63 µm, 60 Å (96W-R10030B)

    SiliaPrep 96 Well Plates, Silica, 40 - 63 µm, 60 Å (96W-R10030B)

    SiliaPrep Silica is the most polar sorbent presenting a slightly acidic character used to extract various compounds from non-polar solvents using hydrogen bonding. Efficient sorbent for the separation of analytes with similar structures and for removing the baseline noise from organic samples.
  50. SiliaPrep 96 Well Plates, C8, 40 - 63 µm, 60 Å (96W-R31030B)

    SiliaPrep 96 Well Plates, C8, 40 - 63 µm, 60 Å (96W-R31030B)

    SiliaPrep C8 is a non-polar sorbent and presents a moderate hydrophobicity. This phase is used to extract extremely non-polar compounds. SiliaPrep C8 is more selective than the C18 phase for compounds such as heavy PAH, vitamins D and oil & greasy compounds.

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