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SiliaPrep SPE & Well Plates, Ion Exchange Phases (IEX)

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SiliCycle offers ion exchange phases providing ion exchange retention mechanisms for the extraction of ionizable compounds from various sample matrices.
Both anion and cation exchange phases are available in SiliaPrep formats for the extraction of acidic and basic analytes respectively.

Available phases:
  • TMA Chloride nec (SAX)
  • TMA Acetate (SAX-2) nec
  • Carbonate
  • Amine (WAX)
  • Tosic Acid (SCX)
  • Propylsulfonic Acid (SCX-2)
  • Carboxylic Acid (WCX)
  • Ion Exchange Kit
  • Piperazine
Available formats:
  • SPE Cartridges
  • Large Reservoir Volume (LRV) SPE Cartridges
  • Mini-SiliaPrep SPE Cartridges
  • 96 Well Plates

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  1. SiliaPrep SPE Cartridges, TMA Chloride (SAX) nec (SPE-R66530B)

    SiliaPrep SPE Cartridges, TMA Chloride (SAX) nec (SPE-R66530B)

    SiliaPrep TMA Chloride (SAX) is a strong anion exchanger sorbent positively charged under all conditions used to extract acid molecules (pKa 3-5).
  2. SiliaPrep 96 Well Plates TMA Chloride nec (SAX), 40 - 63 µm, 60 Å (96W-R66530B)

    SiliaPrep 96 Well Plates TMA Chloride nec (SAX), 40 - 63 µm, 60 Å (96W-R66530B)

    SiliaPrep TMA Chloride (SAX) is a strong anion exchanger sorbent positively charged under all conditions used to extract acid molecules (pKa 3-5).
  3. SiliaPrep SPE Cartridges, TMA Acetate (SAX-2) nec (SPE-R66430B)

    SiliaPrep SPE Cartridges, TMA Acetate (SAX-2) nec (SPE-R66430B)

    SiliaPrep TMA Acetate (SAX-2) is a strong anion exchanger sorbent with a low selectivity acetate counter ion already in place. This sorbent retains more favorably acidic compounds with pKas <5, such as carboxylic acid.
  4. SiliaPrep 96 Well Plates, TMA Acetate (SAX-2) nec, 40 - 63 µm, 60 Å (96W-R66430B)

    SiliaPrep 96 Well Plates, TMA Acetate (SAX-2) nec, 40 - 63 µm, 60 Å (96W-R66430B)

    SiliaPrep TMA Acetate (SAX-2) is a strong anion exchanger sorbent with a low selectivity acetate counter ion already in place. This sorbent retains more favorably acidic compounds with pKas <5, such as carboxylic acid.
  5. SiliaPrep SPE Cartridges, Carbonate (SPE-R66030B)

    SiliaPrep SPE Cartridges, Carbonate (SPE-R66030B)

    SiliaPrep Carbonate (or Si-CO3) is the silica bound equivalent of tetramethyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids, boronic acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions.
  6. SiliaPrep 96 Well Plates, Carbonate, 40 - 63 µm, 60 Å (96W-R66030B)

    SiliaPrep 96 Well Plates, Carbonate, 40 - 63 µm, 60 Å (96W-R66030B)

    SiliaPrep Carbonate (or Si-CO3) is the silica bound equivalent of tetramethyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids, boronic acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions.
  7. SiliaPrep SPE Cartridges Amine (WAX) (SPE-R52030B)

    SiliaPrep SPE Cartridges Amine (WAX) (SPE-R52030B)

    SiliaPrep Amine is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and in normal phase conditions.
  8. SiliaPrep 96 Well Plates Amine (WAX), 40 - 63 µm, 60 Å (96W-R52030B)

    SiliaPrep 96 Well Plates Amine (WAX), 40 - 63 µm, 60 Å (96W-R52030B)

    SiliaPrep Amine is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and in normal phase conditions.
  9. SiliaPrep SPE Cartridges Tosic Acid (SCX) (SPE-R60530B)

    SiliaPrep SPE Cartridges Tosic Acid (SCX) (SPE-R60530B)

    SiliaPrep Tosic Acid (SCX) is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  10. SiliaPrep 96 Well Plates Tosic Acid (SCX), 40 - 63 µm, 60 Å (96W-R60530B)

    SiliaPrep 96 Well Plates Tosic Acid (SCX), 40 - 63 µm, 60 Å (96W-R60530B)

    SiliaPrep Tosic Acid (SCX) is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  11. SiliaPrep SPE Cartridges Propylsulfonic Acid (SCX-2) (SPE-R51230B)

    SiliaPrep SPE Cartridges Propylsulfonic Acid (SCX-2) (SPE-R51230B)

    SiliaPrep Propylsulfonic Acid (SCX-2) is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  12. SiliaPrep 96 Well Plates, Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å (96W-R51230B)

    SiliaPrep 96 Well Plates, Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å (96W-R51230B)

    SiliaPrep Propylsulfonic Acid (SCX-2) is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  13. SiliaPrep SPE Cartridges, Carboxylic Acid (WCX) (SPE-R70030B)

    SiliaPrep SPE Cartridges, Carboxylic Acid (WCX) (SPE-R70030B)

    SiliaPrep Carboxylic Acid is a weak cation exchanger sorbent (WCX) used to extract strong basic compounds.
  14. SiliaPrep 96 Well Plates, Carboxylic Acid (WCX), 40 - 63 µm, 60 Å (96W-R70030B)

    SiliaPrep 96 Well Plates, Carboxylic Acid (WCX), 40 - 63 µm, 60 Å (96W-R70030B)

    SiliaPrep Carboxylic Acid is a weak cation exchanger sorbent (WCX) used to extract strong basic compounds
  15. SiliaPrep SPE Cartridges Amine (WAX) nec (SPE-R52130B)

    SiliaPrep SPE Cartridges Amine (WAX) nec (SPE-R52130B)

    SiliaPrep Amine nec is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and norman phase conditions.
  16. SiliaPrep SPE Cartridges Carboxylic Acid (WCX) nec (SPE-R70130B)

    SiliaPrep SPE Cartridges, Carboxylic Acid (WCX) nec (SPE-R70130B)

    SiliaPrep Carboxilic Acid nec is a weak cation exchanger sorbent (WCX) used to extract strong basics compounds.
  17. SiliaPrep SPE Cartridges Triethylamine (WAX-2) (SPE-R76530B)

    SiliaPrep SPE Cartridges, Triethylamine (WAX-2) (SPE-R76530B)

    SiliaPrep Triethylamine (WAX-2) is a weak anion exchanger that can be used in replacement of SAX and SAX-2 for strong anions to avoid irreversible retention. This phase presents a slightly lower capacity and a moderate non polar character due to the alkyl chain on the amino function. Moreover, it can be employed as metal scavenger and in normal phase conditions.
  18. SiliaPrep 96 Well Plates, Triethylamine (WAX-2), 40 - 63 µm, 60 Å (96W-R76530B)

    SiliaPrep 96 Well Plates, Triethylamine (WAX-2), 40 - 63 µm, 60 Å (96W-R76530B)

    SiliaPrep Triethylamine (WAX-2) is a weak anion exchanger that can be used in replacement of SAX and SAX-2 for strong anions to avoid irreversible retention. This phase presents a slightly lower capacity and a moderate non polar character due to the alkyl chain on the amino function. Moreover, it can be employed as metal scavenger and in normal phase conditions.
  19. SiliaPrep 96 Well Plates, Amine (WAX) nec, 40 - 63 µm, 60 Å (96W-R52130B)

    SiliaPrep 96 Well Plates, Amine (WAX) nec, 40 - 63 µm, 60 Å (96W-R52130B)

    When used at pH ≤ 7.8, Amine is protonated and may be used as a weak anion exchanger (WAX).
  20. SiliaPrep SPE Cartridges Tosic Acid (SCX) nec (SPE-R60430B)

    SiliaPrep SPE Cartridges Tosic Acid (SCX) nec (SPE-R60430B)

    SiliaPrep Tosic Acid is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  21. SiliaPrep 96 Well Plates, Tosic Acid (SCX) nec, 40 - 63 µm, 60 Å (96W-R60430B)

    SiliaPrep 96 Well Plates, Tosic Acid (SCX) nec, 40 - 63 µm, 60 Å (96W-R60430B)

    SiliaPrep Tosic Acid is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  22. SiliaPrep SPE Cartridges Propylsulfonic Acid (SCX-2) nec (SPE-R51430B)

    SiliaPrep SPE Cartridges Propylsulfonic Acid (SCX-2) nec (SPE-R51430B)

    SiliaPrep Propylsulfonic Acid nec is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  23. SiliaPrep 96 Well Plates Propylsulfonic Acid (SCX-2) nec, 40 - 63 µm, 60 Å (96W-R51430B)

    SiliaPrep 96 Well Plates Propylsulfonic Acid (SCX-2) nec, 40 - 63 µm, 60 Å (96W-R51430B)

    SiliaPrep Propylsulfonic Acid nec is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  24. SiliaPrep 96 Well Plates, Carboxylic Acid (WCX) nec, 40 - 63 µm, 60 Å (96W-R70130B)

    SiliaPrep 96 Well Plates, Carboxylic Acid (WCX) nec, 40 - 63 µm, 60 Å (96W-R70130B)

    Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.

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Support Backbone
  1. Silica Gels (24)
Family / Formats
  1. SiliaPrep™ (SPE Cartridges) (24)
Array
  1. Amine (WAX) (6)
  2. Carbonate (CO3) (2)
  3. Carboxylic Acid (WCX) (4)
  4. Propylsulfonic Acid (SCX-2) (4)
  5. TMA Acetate (SAX-2) (2)
  6. TMA Chloride (SAX) (2)
  7. Tosic Acid (SCX) (4)
Pore Size
  1. 60 Å (24)
Endcapping
  1. Endcapped (24)
  2. Non-endcapped (12)
Cartridges Volume
  1. 1 mL (12)
  2. 2 mL (12)
  3. 3 mL (12)
  4. 6 mL (12)
  5. 12 mL (12)
  6. 25 mL (12)
Bed Weight
  1. 50 mg (24)
  2. 100 mg (24)
  3. 200 mg (12)
  4. 500 mg (12)
  5. 1 g (12)
  6. 2 g (12)
  7. 5 g (12)
Particle Size
  1. 40 - 63 µm / 230 - 400 mesh (24)

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