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SiliaBond® HOBt

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SiliaBond® HOBt

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Product Number Quantity  
R70730B-5G 5 g

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R70730B-10G 10 g

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R70730B-25G 25 g

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R70730B-50G 50 g

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R70730B-100G 100 g

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R70730B-250G 250 g

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R70730B-500G 500 g

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R70730B-1KG 1 kg

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Product Description

Specifications


 
  • Details

    Hydroxybenzotriazole (HOBt) has been used for increasing yield and decreasing racemization during chiral amide synthesis. However, dry HOBt can undergo exothermic decomposition. Bonding HOBt to silica eliminates this risk of explosion. SiliaBond® HOBt can be easily activated and should ideally be used with a base such as N,N-diisopropylethylamine in the same condition as in homogeneous solution. Moreover, this supported reagent can be reused a few times without adversely affecting its performance.

  • Additional Information

    Array HOBt
    Family / Formats SiliaBond® (Functionalized Silicas)
    Particle Size 40 - 63 µm / 230 - 400 mesh
    Pore Size 60 Å
    Endcapping Endcapped
    Storage Condition Keep dry, cool (<8°C) and under Argon