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LC-MS Applications

Liquid chromatography-mass spectrometry (LC-MS, or alternatively HPLC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry. LC-MS is a powerful technique used for many applications needing very high sensitivity and specificity.

SiliaChrom® HPLC series are entirely compatible with LC-MS conditions, with low bleeding and minimum concentration buffer needed. SiliaChrom columns give researchers a powerful analytical tool combining the ability of HPLC to separate complex mixtures and the sensitivity and selectivity of mass spectrometry. The fact that LC/MS is also well suited for high sample throughput makes it the analytical tool of choice for drug discovery.

LC-MS Applications:

  • LC-MS Pseudoephedrine in Plasma
  • LC-MS Amlodipine in Bovine Serum
  • LC-MS Propranolol in Bovine Serum
  • LC-MS Hydrochlorothiazide in Human Plasma
  • LC-MS Glipizide in Human Plasma