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Cyano Phases For Separation And Extraction

Cyano (CN) sorbents have been extensively used since the mid 1970 for the separation and extraction of very polar compounds that would normally adsorb irreversibly to more common polar phases such as silica. Previously described as an “universal phase”, the advantage of Cyano phase is its ability to provide chromatographic retention both in normal and reversed-phase separation due to its moderate polarity.

Common applications based on Cyano phases include the separation of flavonoids, extraction of polar compounds from non-polar samples as well as the analysis of samples containing analytes with a wide range of hydrophobicity.

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