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Monomeric Vs. Polymeric C18
For the octadecylsilane stationary phase, SiliCycle proposes two different bonding types: the monomeric and the polymeric functionalized C18.
Silica surface possesses active silanols (Si-OH), which permits the modification of the surface chemistry by grafting silane moieties. This property permits the control of the surface polarity useful in separation techniques. In HPLC, two types of silane are grafted over the surface: chlorodimethylsilane or trichlorosilane.
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