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TFA Removal Using SiliaPrep™ Carbonate

SiliaPrep™ Carbonate (or Si-CO3) is the silica bound equivalent of tetra-methyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions.

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