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CASE STUDY
Scavenging of the Residual Buchwald-Hartwig Catalyst with SiliaMetS® Thiol

The efficiency of the Buchwald-Hartwig catalyst to achieve C-N bond formation makes it very frequently used in organic synthesis, however its high cost and limited supply is less attractive for multigram-scale C−N bond formation. In this article, researchers explored using the catalyst for the C-N cross-coupling of aryl amines with aryl halides in a biphasic aqueous solution. This approach allowed for an efficient synthesis with high yields to be achieved for kilogram-scale reactions.
Find below the list of our various SiliaMetS Thiol products:
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SiliaMetS Thiol (SH) Metal Scavenger (R51030B)
Our most versatile and robust metal scavenger for a variety of metals under a wide range of conditions. Best scavenger for: Ag, Hg, Os, Pd & Ru. Good scavenger for: Cu, Ir, Pb, Rh, Se & Sn. -
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