APPLICATION NOTE
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Comparing Silica and Polymer Supported Products

The use of solid supported scavengers has become a common method for post-synthesis purification. It’s a known fact that the polystyrene backbone greatly influences the behavior of the scavenger in terms of solvent compatibility and reaction rate. On the other hand, silica-bound scavengers, like SiliCycle’s SiliaMetS® and SiliaBond® products, have the advantage of a rigid, non-swelling backbone which eliminates kinetic issues and the need to choose a compatible solvent. Additionally, silica-bound scavengers are easier to handle and weigh due to the absence of static.

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