Efficient Use of E-PAK Technology for the Removal of a Widely Used Suzuki Catalyst

Among the most popular reactions in organic chemistry for carbon-carbon (C-C) bond formation, the Suzuki-Miyaura cross coupling reaction allows the production of various compounds for the pharmaceutical, chemical, drug, agrochemical, and polymer industries. With the new ICH-Q3D guidelines on concentration limits for the residues of metal catalysts, SiliCycle’s chemists compared the efficiency of various metal scavengers in removing traces of one of the most popular Suzuki catalyst, Pd(PPh3)4. All screenings were performed using the MiniBlock apparatus to determine which scavengers were the most successful in removing traces of leftover palladium-catalyst. The main objective was to demonstrate a direct and straightforward transfer to the E-PAK technology.
Find below the list of our various E-PAK cartridges and housing:
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E-PAK Cartridges, Lab Scale, SiliaCarb CA Activated Carbon, 5 x 1 cm
Chemically Activated Carbon -
E-PAK Cartridges, Lab Scale, SiliaCarb VA Activated Carbon, 5 x 1 cm
Vegetable Activated Carbon -
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E-PAK Cartridges, Lab Scale, SiliaCarb VW Activated Carbon, 5 x 1 cm
Virgin Wood Activated Carbon -
Commercial Scale SiliaMetS E-PAK Cartridges, 16.5 x 100 cm
E-PAK commercial scale cartridges with silica-based metal scavenger: SiliaMets Thiol or SiliaMetS DMT -
Commercial Scale SiliaMetS E-PAK Cartridges, 16.5 x 50 cm, 1/box
E-PAK commercial scale cartridges with silica-based metal scavenger: SiliaMets Thiol or SiliaMetS DMT -
Pilot Scale SiliaMetS E-PAK Cartridges, 16.5 x 25 cm, 1/box
E-PAK pilot scale cartridges with silica-based metal scavenger: SiliaMets Thiol or SiliaMetS DMT -
Pilot Scale SiliaMetS E-PAK Cartridges, 16.5 x 12.5 cm, 1/box
E-PAK pilot scale cartridges with silica-based metal scavenger: SiliaMets Thiol or SiliaMetS DMT -
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E-PAK Cartridges, Lab Scale, SiliaCarb CA Activated Carbon, 5 x 10 cm
Chemically Activated Carbon -
E-PAK Cartridges, Lab Scale, SiliaCarb VA Activated Carbon, 5 x 10 cm
Vegetable Activated Carbon -
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E-PAK Cartridges, Lab Scale, SiliaCarb VW Activated Carbon, 5 x 10 cm
Virgin Wood Activated Carbon -
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E-PAK Cartridges, Lab Scale, SiliaCarb CA Activated Carbon, 5 x 25 cm
Chemically Activated Carbon -
E-PAK Cartridges, Lab Scale, SiliaCarb VA Activated Carbon, 5 x 25 cm
Vegetable Activated Carbon -
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E-PAK Cartridges, Lab Scale, SiliaCarb VW Activated Carbon, 5 x 25 cm
Virgin Wood Activated Carbon -
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Housing Kit for Laboratory Scale E-PAK Cartridges, with 2 bowls (LSHK-110)
Lab scale housing kit including 2 bowls: 5 x 1 & 5 x 10 cm. -
Housing Kit for Laboratory Scale E-PAK Cartridges, with 2 bowls (LSHK-125)
Lab scale housing kit including 2 bowls: 5 x 1 & 5 x 25 cm. -
Housing Kit for Laboratory Scale E-PAK Cartridges, with 3 bowls (LSHK-11025)
Lab scale housing kit including 3 bowls: 5 x 1 ; 5 x 10 & 5 x 25 cm. -
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E-PAK Cartridges, SiliaMetS Diamine, 5 x 1 cm
Best scavenger for: Cr, Pd, Pt, W & Zn / Good scavenger for: Cd, Co, Cu, Fe, Hg, Ni, Pb, Ru, Sc, Se & V