Efficient use of the E-PAK technology for removing iridium

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Catalytic hydrogenation of double bonds is one of the most common and studied reactions in chemistry. Some of the most complex hydrogenations involve the creation of a chiral center from an alkene. In the early 70’s, Crabtree and co-workers developed an iridium based catalyst for the asymmetric hydrogenations of mono-, di-, tri-, and tetrasubstituted alkenes with high enantioselectivity. Since its first report, several iterations of Crabtree’s catalyst have been synthesized with different ligands. This catalyst is now used in various industrial processes and one of the challenges is to be able to remove the iridium after the reaction.

In this Application Note, the scavenging efficiency of activated carbons and of the SiliaMetS portfolio, as well as their use in E-PAK cartridges for the removal of iridium is showcased.

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