APPLICATION NOTE
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Scavenging Using SiliaBond Carbonate

SiliaBond Carbonate (Si-CO3) is the silica bound equivalent of Tetramethylammonium Carbonate. This sorbent can be used as a general base to quench a reaction, to freebase amines from their ammonium salt form as well as to scavenge acids and acidic phenols. This Application Note explores some of these applications in more detail.

Find below the list of SiliCycle's products involved in this Application Note:
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SiliaBond Carbonate (CO3) (R66030B)
SiliaBond Carbonate (Si-CO3) is the silica bound equivalent of tetramethyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions. -
SiliaPrep SPE Cartridges, Carbonate (SPE-R66030B)
SiliaPrep Carbonate (or Si-CO3) is the silica bound equivalent of tetramethyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids, boronic acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions. -
SiliaPrep 96 Well Plates, Carbonate, 40 - 63 µm, 60 Å (96W-R66030B)
SiliaPrep Carbonate (or Si-CO3) is the silica bound equivalent of tetramethyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids, boronic acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions. -
SiliaSep OT Flash Cartridges, Carbonate, 40 - 63 µm, 60 Å (FLH-R66030B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument.