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 CASE STUDY 

A Practical Cleavage of Acetals Using SiliaMetS® Thiol

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Removing protecting groups from a synthesis pathway can prove difficult. In order to overcome this challenge, a method using SiliaMetS Thiol was developed for the deprotection of various aromatic and aliphatic acetals to their corresponding catechol or diol derivatives.

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  1. SiliaMetS Thiol (SH) (R51030B)

    SiliaMetS Thiol (SH) Metal Scavenger (R51030B)

    Our most versatile and robust metal scavenger for a variety of metals under a wide range of conditions. Best scavenger for: Ag, Hg, Os, Pd & Ru. Good scavenger for: Cu, Ir, Pb, Rh, Se & Sn.
  2. SiliaSphere Spherical Silica Gels, Thiol, 10 µm, 100 Å (S51007E-A)

    SiliaSphere Spherical Silica Gels, Thiol, 10 µm, 100 Å (S51007E-A)

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  3. SiliaSep Flash Cartridges, Thiol, 40 - 63 µm, 60 Å (FLH-R51030B)

    SiliaSep Flash Cartridges, Thiol, 40 - 63 µm, 60 Å (FLH-R51030B)

    Thiol is our most versatile and robust metal scavenger for a variety of metals under a wide range of conditions. Best scavenger for: Ag, Hg, Os, Pd & Ru. Good scavenger for: Cu, Ir, Pb, Rh & Sn.
  4. Laboratory Scale SiliaMetS® Thiol E-PAK® Cartridges for metal purification

    E-PAK Cartridges, SiliaMetS Thiol, 5 x 1 cm (LS-R51030B-1CM)

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  5. Laboratory Scale SiliaMetS Thiol E-PAK Cartridges, 5 x 10 cm

    E-PAK Cartridges, SiliaMetS Thiol, 5 x 10 cm (LS-R51030B-10CM)

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  6. Laboratory Scale SiliaMetS Thiol E-PAK® 5 x 25 cm Cartridges for metal removal

    E-PAK Cartridges, SiliaMetS Thiol, 5 x 25 cm (LS-R51030B-25CM)

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  7. SiliaPrep SPE Cartridges Thiol (SPE-R51030B)

    SiliaPrep SPE Cartridges Thiol (SPE-R51030B)

    Best scavenger for: Ag, Hg, Os, Pd & Ru / Good scavenger for: Cu, Ir, Pb, Rh & Sn
  8. SiliaSep OT Flash Cartridges (Open Top), Thiol, 40 - 63 µm, 60 Å (FLH-R51030B-OT)

    SiliaSep OT Flash Cartridges (Open Top), Thiol, 40 - 63 µm, 60 Å (FLH-R51030B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Thiol is our most versatile and robust metal scavenger for a variety of metals under a wide range of conditions. Best scavenger for: Ag, Hg, Os, Pd & Ru. Good scavenger for: Cu, Ir, Pb, Rh & Sn
  9. SiliaChrom Plus HPLC Guard Cartridges, Palladium Scavenger (DMT + Thiol), 5 µm (HPLG-K34605E-A)

    SiliaChrom Plus HPLC Guard Cartridges, Palladium Scavenger (DMT + Thiol), 5 µm (HPLG-K34605E-A)

    Crude reaction mixtures can directly be injected without further metal removal: these Palladium Scavenging Guard Cartridges will protect your SiliaChrom Plus HPLC column and your system from damageable metallic impurities.
  10. SiliaPrep 96 Well Plates, Thiol, 40 - 63 µm, 60 Å (96W-R51030B)

    SiliaPrep 96 Well Plates, Thiol, 40 - 63 µm, 60 Å (96W-R51030B)

    SiliaMetS® Thiol (Si-Thiol) is our most versatile and robust metal scavenger for a variety of metals under a wide range of conditions. Best scavenger: Ag, Hg, Os, Pd & Ru. Good scavenger: Cu, Ir, Pb, Rh & Sn.
  11. SiliaChrom Plus HPLC Guard Cartridges, Palladium Scavenger (DMT + Thiol), 10 µm (HPLG-K34607E-A)

    SiliaChrom Plus HPLC Guard Cartridges, Palladium Scavenger (DMT + Thiol), 10 µm (HPLG-K34607E-A)

    Crude reaction mixtures can directly be injected without further metal removal: these Palladium Scavenging Guard Cartridges will protect your SiliaChrom Plus HPLC column and your system from damageable metallic impurities.

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SiliaSep PREMIUM - Flash Cartridges packed with Spherical Silica
E-PAK® - Fixed Bed Flow-through Purification Cartridges

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