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Gain insight into the world of purification with this collection of articles

 

Loading in Progress – Avoiding loading capacity mistakes

Friday, March 4, 2022 9:31:54 AM America/New_York

With flash chromatography, you either want to yield a large quantity of product or you want it extremely pure. When both are simultaneously true, a large loading capacity is your best friend. It simplifies the purification of all your crude product in a single run, with high yield and high purity. So, what exactly is loading capacity? Read More
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Loading in progress – Techniques for Successful Sample Loadings

Friday, March 4, 2022 9:31:48 AM America/New_York

Every researcher has their own shortcuts to make things easier and faster in the lab. Unfortunately, when it comes to running flash separations, most of the time there is no way to be sneaky and just load the sample without considering the options and still results in a good separation. And the little of the time it does work, is a lot of luck. Sample load is one of those traps that make us lose more time and energy (and money) neglecting the loading aspect of chromatography. Read More
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The secrets of the Certificates of Analysis revealed

Monday, January 10, 2022 10:37:55 AM America/New_York

In industry, the most common way to demonstrate consistent quality from the product you are getting from the manufacturer is with the Certificate of Analysis (also known as COA or a CofA) Read More
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Troubleshooting for Thin Layer Chromatography

Wednesday, December 8, 2021 2:54:43 PM America/New_York

Thin layer chromatography (TLC) sounds like a relatively simple process. However, in practice, separating the different components can be surprisingly tricky... Read More
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Based on a proactive approach to pollution prevention, the concept, which has evolved with the increased awareness of the effects of chemical contaminants on the planet's health, is revolutionizing industrial chemistry. Read More
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How to Solve Common Challenges in Solid-Phase Extraction

Monday, October 18, 2021 3:38:42 PM America/New_York

Sample preparation is the under-appreciated workhorse of the analytical chemistry lab. In fact, 60-80% of an analyst’s time is devoted to this! Selecting the most appropriate sample preparation tools for analysis and understanding the proper techniques in addition to common challenges are well worth an analyst’s investment of time. Read More

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How to Streamline Metal Scavenger Scale-Up During Drug Development

Monday, September 20, 2021 3:38:28 PM America/New_York

Customers and process scientists have concerns about the scalability of metal scavengers for drug synthesis – a topic we’ve touched on before in other posts but haven’t yet fully explored... Read More
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Thin Layer Chromatography Plates: Use and Best Practices

Monday, August 16, 2021 9:53:36 AM America/New_York

We usually think of chromatography in terms of columns or capillaries, but separations can also be carried out on a planar surface by means of thin-layer chromatography (TLC). It is widely employed in reaction monitoring, screening, sample purification, and compound purity evaluation. Read More
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The Role of Functionalized Silica in Chromatography and Organic Synthesis

Tuesday, July 20, 2021 12:36:25 PM America/New_York

When we think of silica, we’re familiar with products such as glass, silica gels, and desiccants. It is also widely used in pharmaceutical development, food and cosmetic production, as well as semiconductor manufacturing and other industries. Read More
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What You Need to Know About Cannabis Industry Testing and Analysis

Tuesday, June 15, 2021 3:27:55 PM America/New_York

As of this past May, Canada and 36 U.S. states have legalized medical or recreational marijuana. Predictably, as more countries are becoming open to legalizing cannabis, regulations are slowly following suit to ensure adequate product safety and quality. Read More
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