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Product Blog

Gain insight into the world of purification with this collection of articles

 

What Zombies Can Teach You About Chromatography

Monday, August 1, 2022 12:50:38 PM America/New_York

Summer is finally here, and it is time to catch up on your to-be-read pile. I know you have been meaning to read (or read again) some basic info on chromatographicy sorbents, but there was just not enough time. Fear not and let me (not zombies, sorry...) summarize the most important info from our previous blog articles on the fundamentals of chromatography so you can relax while lounging by the pool. Read More
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Functionalized Silica Is Exactly What Your Industry Is Looking For

Tuesday, May 31, 2022 8:00:00 PM America/New_York

Whatever your industry, we’ve got you covered for your purification needs. From drug development to food products, I extracted some highlights of our most recent blog articles on relevant industrial processes that have to do with achieving your purity goals Read More
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10 Things You Should Know About Metal Scavenging

Monday, May 30, 2022 2:40:44 PM America/New_York

You’ve probably already heard a lot of things about Metal Scavengers. You might know how their usefulness is unquestionable in removing metal impurities and that they work selectively to react and bind to excess metal complexes. Let’s review the other important facts and learn more with this list of 10 things you should know about metal scavenging. Read More
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It’s not just about the shape – Handy guide to (other) common problems in HPLC

Thursday, April 21, 2022 2:12:18 PM America/New_York

Not everything is about shape when it comes to chromatograms. To get faster and more confident at troubleshooting your HPLC technique, you need to learn how to recognize other indicators that tell you when there is a problem. Read More
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Before getting into the six most common shape problems, it is important to know why it matters. If a peak becomes too broad or its tail is too large, it might overlap with or hide another peak. In the case of preparative chromatography, this also means mixed fractions are collected. Read More
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As everyone in R&D knows, pharmaceutical process scalability can be challenging and stressful. Now that I know better, I am sharing how to excel at scaling-up purifications and eliminate the concerns of having large scales results mirroring those from the lab bench. Read More
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Loading in Progress – Avoiding loading capacity mistakes

Friday, March 4, 2022 9:31:54 AM America/New_York

With flash chromatography, you either want to yield a large quantity of product or you want it extremely pure. When both are simultaneously true, a large loading capacity is your best friend. It simplifies the purification of all your crude product in a single run, with high yield and high purity. So, what exactly is loading capacity? Read More
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Loading in progress – Techniques for Successful Sample Loadings

Friday, March 4, 2022 9:31:48 AM America/New_York

Every researcher has their own shortcuts to make things easier and faster in the lab. Unfortunately, when it comes to running flash separations, most of the time there is no way to be sneaky and just load the sample without considering the options and still results in a good separation. And the little of the time it does work, is a lot of luck. Sample load is one of those traps that make us lose more time and energy (and money) neglecting the loading aspect of chromatography. Read More
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The secrets of the Certificates of Analysis revealed

Monday, January 10, 2022 10:37:55 AM America/New_York

In industry, the most common way to demonstrate consistent quality from the product you are getting from the manufacturer is with the Certificate of Analysis (also known as COA or a CofA) Read More
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Troubleshooting for Thin Layer Chromatography

Wednesday, December 8, 2021 2:54:43 PM America/New_York

Thin layer chromatography (TLC) sounds like a relatively simple process. However, in practice, separating the different components can be surprisingly tricky... Read More
0 Comments | Posted in Product Blog By SiliCycle