SiliaSep - Flash Cartridges
Flash Cartridges Portfolio Cartridges Characteristics
With SiliaSep, benefit from the same quality that all our products are known for: selectivity, speed & reliability.
With a more tightly packed silica bed and a homogeneous packing, the use of pre-packed flash cartridges improves purification efficiency by offering superior reproducibility and productivity compared to conventional manual flash chromatography.
SiliaSep cartridges are available in two silica gel grades:
and with various functionalities:
SiliaSep Flash Cartridge Overview
Our flash chromatography products offer high levels of performance and reproducibility. The flash media consistently has a tight particle size distribution with low fines and extremely low metal ion content, for more predictable and easier separations.
Using SiliCycle SiliaSep cartridges, you can purify your sample base on different mechanisms depending on the properties or your compound. Because we can provide cartridges packed with our SiliaBond® functionalized silica gel, you can choose exactly the cartridge that will fit your need.
SiliaSep Cartridges Compatibility
To better suit your needs, the SiliaSep flash cartridges family includes 4 types of cartridges that are compatible with different types of instruments:
Type | Compatibility |
---|---|
SiliaSep & SiliaSep PREMIUM | Teledyne Isco™, Biotage™, Varian / Analogix™, Grace Reveleris™, Büchi, Gilson & Interchim / Armen |
SiliaSep XL | Isco CombiFlash Companion XL. Note: for SiliaSep XL cartridges (800 g and 1,600 g), you may need to use an XL Adapter. |
SiliaSep OT | FlashMaster™ |
SiliaSep Reproducibility
SiliaSep Flash Cartridges offer incredible performance over competitive products due to the higher silica gel quality and innovative packing technology. Both cartridge series allow superior results and can be considered the products of choice for all purification needs.
SiliaSep XL - Superior Resolution
SiliCycle evaluated the performance of the SiliaSep XL cartridges compared to a well-known brand. For both sizes, SiliaSep XL outperforms the competition.
SiliaSep XL 800 g
SiliaSep XL 1 600 g
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SiliaSep PREMIUM Flash Cartridges, SCX-2 (Propylsulfonic Acid), 25 µm, 90 Å (FLH-51295D-A)
Due to the very low pKa (< 1) these functions are strong cation exchangers since they maintain a negative charge throughout the pH scale. The most common use is likely for catch and release purification of weak cations (for example basic drugs and analgesics), analysis of basic biomolecules (peptides and proteins) and water-soluble vitamins (basic vitamins B and C). -
SiliaSep PREMIUM Flash Cartridges, SCX (Tosic Acid), 25 µm, 90 Å (FLH-60595D-A)
Due to the very low pKa (< 1) these functions are strong cation exchangers since they maintain a negative charge throughout the pH scale. The most common use is likely for catch and release purification of weak cations (for example basic drugs and analgesics), analysis of basic biomolecules (peptides and proteins) and water-soluble vitamins (basic vitamins B and C). -
SiliaSep PREMIUM Flash Cartridges SAX-2 nec (TMA Acetate), 25 µm, 90 Å (FLH-66495D-A)
The acetate counter-ion is easily exchangeable (more than the chloride ion) for compounds with pKa < 5, such as carboxylic acids. This phase can be used in organic chemistry applications to selectively purify acidic compounds or remove acidic impurities from reaction mixtures. -
SiliaSep PREMIUM Flash Cartridges SAX nec (TMA Chloride), 25 µm, 90 Å (FLH-66595D-A)
The quaternary amine is permanently charged (pH independent). It is commonly used for the extraction of weak anions (such as carboxylic acids) that may not bind strongly enough to weaker anion exchangers. Analysis of acidic drugs and analgesics, biomolecules (peptides and proteins) and water-soluble vitamins (vitamins B and C). -
SiliaSep PREMIUM Flash Cartridges, Cyano (CN), 25 µm, 90 Å (FLH-38095D-A)
Versatile sorbent that can be used either as normal or reversed-phase. Indicated for products with intermediate to extreme polarity. The slightly hydrophobic nature of the cyano group offers alternative selectivity. -
SiliaSep PREMIUM Flash Cartridges, Pentafluorophenyl (PFP), 25 µm, 90 Å (FLH-67595D-A)
For a new selectivity approach with aromatic ring interactions, or for the purification of conjugated compounds (isomers). -
SiliaSep PREMIUM Flash Cartridges, Phenyl, spherical, 25 µm, 90 Å (FLH-34095D-A)
Moderate non-polar sorbent with different selectivity for aromatic compounds compared to other non-polar sorbents. -
SiliaSep PREMIUM Flash Cartridges, C4, spherical, 25 µm, 90 Å (FLH-32095D-A)
Presents less retention compared to C18 and C8. Widely used for molecules with large hydrophobic regions. -
SiliaSep OT Flash Cartridges, C18 (17%), 40 - 63 µm, 60 Å (FLH-R00230B-OT)
SiliaPrep C18 (17%) is a strongly hydrophobic and non polar sorbent. It is very useful for the extraction of acidic / neutral / basic compounds from aqueous solutions, organic compounds from water and drugs & metabolites from fluids. -
SiliaSep Flash Cartridges, WCX, 40 - 63 µm, 60 Å (FLH-R70030B)
A weak cation exchanger with a pKa of 4.8. A pH of 2.8 or below is needed to neutralize the phase and easily elute strong cationic analytes that are neutralized only at extreme basic conditions. This phase is commonly used for the extraction of strong cationic species, which would bind too strongly to strong cation exchangers. -
SiliaSep PREMIUM Flash Cartridges, Amine (WAX), spherical 25 µm (FLH-52095D-A)
The amine phase can be used either in normal phase for the purification of compounds with basic properties & for monosaccharides separation; or as a weak anion exchanger (pKa of 9.8). At pH 7.8 or below, the functional groups are positively charged. It facilitates the rapid release of very strong anions such as sulfonic acids that may be too strongly retained on SAX.
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SiliaSep PREMIUM Flash Cartridges, C8, spherical 25 µm (FLH-30895D-A)
Presents less retention compared to C18. Typically used for highly hydrophobic pesticides, small peptides and large molecule drugs. -
SiliaSep Flash Cartridges, AMPA, 40 - 63 µm, 60 Å (FLH-R85130B)
SiliaMetS AMPA is is a silica-supported aminomethylalkylphosphonic acid ligand known for its excellent metal-bonding properties. Best scavenger for: Al, Ce, Gd, La, Ni, Sb & V. Good scavenger for: Co, Cu, Fe, Mg, & Zn -
SiliaSep PREMIUM Flash Cartridges, Diol, spherical 25 µm (FLH-35095D-A)
Good alternative for difficult separation of low to medium polarity samples. Useful for mono and polysaccharides separation. Can be used in HILIC mode. -
SiliaSep OT Flash Cartridges (Open Top), Diamine, 40 - 63 µm, 60 Å (FLH-R49030B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Cr, Pd, Pt, W & Zn. Good scavenger for: Cd, Co, Cu, Fe, Hg, Ni, Pb, Ru & Sc. -
SiliaSep OT Flash Cartridges (Open Top), Triamine, 40 - 63 µm, 60 Å (FLH-R48030B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Cr, Pd, Pt, W & Zn. Good scavenger for: Ag, Cd, Co, Cu, Fe, Hg, Ni, Os, Pb, Rh, Ru & Sc. -
SiliaSep OT Flash Cartridges (Open Top), Imidazole, 40 - 63 µm, 60 Å (FLH-R79230B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Cd, Co, Cu, Fe, Ir, Li, Mg, Ni, Os, W & Zn. Good scavenger for: Cr, Pd & Rh. -
SiliaSep OT Flash Cartridges (Open Top), TAAcONa, 40 - 63 µm, 60 Å (FLH-R69230B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Ca, Cd, Cs, Cu, Fe, Ir, La, Li, Mg, Ni, Os, Rh, Sc & Sn. Good scavenger for: Cr, Pd, Ru, Se & Zn. -
SiliaSep OT Flash Cartridges (Open Top), Thiourea, 40 - 63 µm, 60 Å (FLH-R69530B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Pd & Ru. Good scavenger for: Ag, Cu, Fe, Os, Rh, Sc & Sn. -
SiliaSep OT Flash Cartridges (Open Top), DMT, 40 - 63 µm, 60 Å (FLH-R79030B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Ir, Ni, Os, Pd, Pt, Rh, Se & Ru. Good scavenger for: Cd, Co, Cu, Fe, Sc & Zn -
SiliaSep OT Flash Cartridges (Open Top), Cysteine, 40 - 63 µm, 60 Å (FLH-R80530B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Cd, Fe, Ir, Os, Ru, Sc & Sn. Good scavenger for: Ca, Cr, Cs, Cu, La, Mg, Pd, Pt, Rh, Se & Zn -
SiliaSep OT Flash Cartridges (Open Top), TAAcOH, 40 - 63 µm, 60 Å (FLH-R69030B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Ca, Co, Ir, Li, Mg, Ni, Os, Ru & Sc. Good scavenger for: Cr, Cs, Fe, Pd, Rh & Sn -
SiliaSep Flash Cartridges, Imidazole, 40 - 63 µm, 60 Å (FLH-R79230B)
Imidazole is a versatile metal scavenger for a variety of metals, under a wide range of conditions, and the preferred metal scavenger for iron catalysts. Imidazole can also be used as an amine base in systems that are generally sensitive to basic conditions compared to other SiliaMetS supported bases. Best scavenger for: Cd, Co, Cu, Fe, Ir, Li, Mg, Ni, Os, W & Zn. Good scavenger for: Cr, Pd & Rh. -
SiliaSep Flash Cartridges, WAX-2, 60 Å, 40 - 63 µm, 60 Å (FLH-R76530B)
With a pKa of 10.5, this phase is preferred over SAX when performing catch and release purification of compounds bearing a permanent negative charge. -
SiliaSep Flash Cartridges, Pentafluorophenyl (PFP), 40 - 63 µm, 60 Å (FLH-R67530B)
For a new selectivity approach with aromatic ring interactions, or for the purification of conjugated compounds (isomers). -
SiliaSep Flash Cartridges, Phenyl, 40 - 63 µm, 60 Å (FLH-R34030B)
Moderate non-polar sorbent with different selectivity for aromatic compounds compared to other non-polar sorbents. -
SiliaSep Flash Cartridges, C4, 40 - 63 µm, 60 Å (FLH-R32030B)
Presents less retention compared to C18 and C8. Widely used for molecules with large hydrophobic regions. -
SiliaSep Flash Cartridges, C8, 40 - 63 µm, 60 Å (FLH-R30830B)
Presents less retention compared to C18. Typically used for highly hydrophobic pesticides, small peptides and large molecule drugs. -
SiliaSep Flash Cartridges, Silver Nitrate (AgNO3), 40 - 63 µm, 60 Å (FLH-R23530B)
Mainly used for the separation of cis / trans isomers of unsaturated compounds such as alkenes, lipids, steroids and terpenes. -
SiliaSep Flash Cartridges, Basic Alumina, 50 - 75 µm, 60 Å (FLH-AUT-0055)
Good retention of aromatic compounds, aliphatic amines and compounds containing electronegative functions. -
SiliaSep Flash Cartridges, Neutral Alumina, 50 - 75 µm, 60 Å (FLH-AUT-0054)
Good retention of aromatic compounds, aliphatic amines and compounds containing electronegative functions. -
SiliaSep Flash Cartridges, Acidic Alumina, 50 - 75 µm, 60 Å (FLH-AUT-0053)
Good retention of aromatic compounds, aliphatic amines and compounds containing electronegative functions. -
SiliaSep PREMIUM Flash Cartridges, Silica, spherical 25 µm (FLH-10095D-A)
Most popular sorbent for day-to-day use for the purification of non-ionic polar organic compounds. -
SiliaSep PREMIUM Flash Cartridges, C18, spherical 25 µm (FLH-03295D-A)
Indicated for the purification of low to high polarity compounds. Provides reproducible purification without the complexity and cost of preparative HPLC. -
SiliaSep Pre-Packed Solid-Load Cartridges, Amine (WAX) (SPL-R52030B)
Designed to be used with SiliaSep flash cartridges for sample loading by liquid injection -
SiliaSep Pre-packed Solid-Load Cartridges, Silica (SPL-R10030B)
Designed to be used with SiliaSep flash cartridges for sample loading by liquid injection -
SiliaSep OT Flash Cartridges, Fluorochrom, 25 g, 150 mL, 40 - 63 µm, 60 Å (FLH-R63730B-OT)
SiliaSep OT flash cartridges are compatible with FlashMaster instruments. Indicated for the purification of fluorous compounds. They provide reproducible purification without the complexity and cost of preparative HPLC. -
SiliaSep OT Flash Cartridges (Open Top), Thiol, 40 - 63 µm, 60 Å (FLH-R51030B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Thiol is our most versatile and robust metal scavenger for a variety of metals under a wide range of conditions. Best scavenger for: Ag, Hg, Os, Pd & Ru. Good scavenger for: Cu, Ir, Pb, Rh & Sn -
SiliaSep OT Flash Cartridges, Carbonate, 40 - 63 µm, 60 Å (FLH-R66030B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument. -
SiliaSep OT Flash Cartridges (Open Top), TMA Acetate (SAX-2) nec, 40 - 63 µm, 60 Å (FLH-R66430B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument. The acetate counter-ion is easily exchangeable (more than the chloride ion) for compounds with pKa < 5, such as carboxylic acids. This phase can be used in organic chemistry applications to selectively purify acidic compounds or remove acidic impurities from reaction mixtures. -
SiliaSep OT Flash Cartridges (Open Top), TMA Chloride (SAX) nec, 40 - 63 µm, 60 Å (FLH-R66530B-OT)
SiliaSep OT flash cartridges, compatible with FlashMaster instrument. The quaternary amine is permanently charged (pH independent). It is commonly used for the extraction of weak anions (such as carboxylic acids) that may not bind strongly enough to weaker anion exchangers. Analysis of acidic drugs and analgesics, biomolecules (peptides and proteins) and water-soluble vitamins (vitamins B and C). -
SiliaSep OT Flash Cartridges, Tosic Acid (SCX), 40 - 63 µm, 60 Å (FLH-R60530B-OT)
SiliaSep OT flash cartridges, compatible with any FlashMaster instrument. Strong cation exchangers since they maintain a negative charge throughout the pH scale. Most common use is likely for catch and release purification of weak cations, analysis of basic biomolecules and water-soluble vitamins -
SiliaSep OT Flash Cartridges (Open Top), Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å (FLH-R51230B-OT)
SiliaSep OT flash cartridges, compatible with any FlashMaster instrument. Strong cation exchangers since they maintain a negative charge throughout the pH scale. Most common use is likely for catch and release purification of weak cations, analysis of basic biomolecules and water-soluble vitamins -
SiliaSep OT Flash Cartridges (Open Top), Diol nec, 40 - 63 µm, 60 Å (FLH-R35030B-OT)
SiliaSep OT flash cartridges, compatible with any FlashMaster instrument. Good alternative for difficult separation of low to medium polarity samples. Useful for mono and polysaccharides separation. Can be used in HILIC mode.