Product Blog

The importance of removing residual metallic impurities from pharmaceutical products before commercialization is no surprise to anyone in the industry. These elemental impurities are known to cause health concerns and as such, are controlled by guidelines for their trace residue in pharmaceutical products. Read More

Activated carbons are known to be an efficient way to remove impurities, such as unwanted colors, odors, and precious metal catalysts. Since they are not as selective as SiliaMetS metal scavengers for metal removal, they are most often used as a pre-treatment to reduce the overall quantities of impurities, which helps achieving desired levels of residual impurities. Read More

In organic synthesis, using excess reagents is a common strategy to maximize the conversion and product yield as this increases the probability of collisions between the desired functions. However, by using excess reagents you are guaranteed to have organic impurities from the unreacted reagents in your crude product. Read More

Catalysis is common across industries, and it is estimated that over 90 % of commercial goods are made using catalysts during some point of their manufacturing. For a process that is so widely used, you might still have some questions but not to worry, we have some answers. Read More

Summer is finally here, and it is time to catch up on your to-be-read pile. I know you have been meaning to read (or read again) some basic info on chromatographicy sorbents, but there was just not enough time. Fear not and let me (not zombies, sorry...) summarize the most important info from our previous blog articles on the fundamentals of chromatography so you can relax while lounging by the pool. Read More

Whatever your industry, we’ve got you covered for your purification needs. From drug development to food products, I extracted some highlights of our most recent blog articles on relevant industrial processes that have to do with achieving your purity goals Read More

You’ve probably already heard a lot of things about Metal Scavengers. You might know how their usefulness is unquestionable in removing metal impurities and that they work selectively to react and bind to excess metal complexes. Let’s review the other important facts and learn more with this list of 10 things you should know about metal scavenging. Read More

Not everything is about shape when it comes to chromatograms. To get faster and more confident at troubleshooting your HPLC technique, you need to learn how to recognize other indicators that tell you when there is a problem. Read More

Before getting into the six most common shape problems, it is important to know why it matters. If a peak becomes too broad or its tail is too large, it might overlap with or hide another peak. In the case of preparative chromatography, this also means mixed fractions are collected. Read More

As everyone in R&D knows, pharmaceutical process scalability can be challenging and stressful. Now that I know better, I am sharing how to excel at scaling-up purifications and eliminate the concerns of having large scales results mirroring those from the lab bench. Read More