Product Blog
Gain insight into the world of purification with this collection of articles
How to Streamline Metal Scavenger Scale-Up During Drug Development
Monday, September 20, 2021 3:38:28 PM America/New_York
Customers and process scientists have concerns about the scalability of metal scavengers for drug synthesis – a topic we’ve touched on before in other posts but haven’t yet fully explored... Read More
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By SiliCycle
Thin Layer Chromatography Plates: Use and Best Practices
Monday, August 16, 2021 9:53:36 AM America/New_York
We usually think of chromatography in terms of columns or capillaries, but separations can also be carried out on a planar surface by means of thin-layer chromatography (TLC). It is widely employed in reaction monitoring, screening, sample purification, and compound purity evaluation. Read More
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By SiliCycle
The Role of Functionalized Silica in Chromatography and Organic Synthesis
Tuesday, July 20, 2021 12:36:25 PM America/New_York
When we think of silica, we’re familiar with products such as glass, silica gels, and desiccants. It is also widely used in pharmaceutical development, food and cosmetic production, as well as semiconductor manufacturing and other industries. Read More
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By SiliCycle
What You Need to Know About Cannabis Industry Testing and Analysis
Tuesday, June 15, 2021 3:27:55 PM America/New_York
As of this past May, Canada and 36 U.S. states have legalized medical or recreational marijuana. Predictably, as more countries are becoming open to legalizing cannabis, regulations are slowly following suit to ensure adequate product safety and quality. Read More
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By SiliCycle
Use of Silica in Chromatography: Understanding Key Physical Characteristics
Tuesday, May 11, 2021 11:13:35 AM America/New_York
Which characteristics are important when selecting a silica product for a chromatographic application? Here’s a rundown of key attributes and why each one may prove pivotal in your separation... Read More
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By SiliCycle
How to Choose the Right Chromatographic Phase?
Monday, April 26, 2021 2:38:03 PM America/New_York
Selecting the right phase demands consideration of the application, column chemistry, separation mode and particle morphology. In this article, we’ll share a basic roadmap for chromatographers to follow in order to accelerate your efforts and (hopefully) reduce or eliminate tedious guesswork. Read More
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By SiliCycle
Simplifying Metal Catalyst Removal in Drug Development Applications
Friday, March 26, 2021 2:55:53 PM America/New_York
In recent years, regulatory agencies have zeroed in on the presence of heavy metals in pharmaceutical and biopharmaceutical drug substances. The result has been more stringent regulation of allowable metal content in APIs. Read More
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By SiliCycle
How to Use Metal Scavengers to Eliminate Metal Contamination in Drugs
Saturday, December 12, 2020 12:25:31 PM America/New_York
The term "metal scavengers" might call up images of strolling along a sunny beach, metal detector in hand, hunting for gold among glittering grains of sand. But in the context of chemistry, the "beach" is a drug and the "metal detectors" are silica gels. Metal scavengers are functionalized silica gels designed to react and bind excess metal complexes. They are essential to public health. Read More
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By SiliCycle
Stop Optimizing, Start Innovating with New Automated Chemical Synthesis System
Tuesday, February 5, 2019 7:00:00 AM America/New_York
MIT researchers have developed an automated chemical synthesis system that aims at freeing up synthetic chemists for them to spend time on what really matters: innovation, creativity, discovery and development... Read More
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By SiliCycle
Paper on advanced sol-gel materials published in Chemical Reviews
Thursday, July 4, 2013 11:45:07 AM America/New_York
Chemical Reviews, the world’s highest-ranked chemistry journal, has published the article entitled “The Sol-Gel Route to Advanced Silica-Based Materials and Recent Applications” co-authored by Italy’s research chemists Mario Pagliaro and Rosaria Ciriminna, by Portugal`s chemistry professors Laura Ilharco and Alexandra Fidalgo, and by Quebec`s industrial researchers François Béland and Valerica Pandarus... Read More